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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine



   african trypanosomiasis
  

Disease ID 784
Disease african trypanosomiasis
Definition
A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces "African sleeping sickness." Nagana is a rapidly fatal trypanosomiasis of horses and other animals.
Synonym
[x]african trypanosomiasis, unspecified
[x]african trypanosomiasis, unspecified (disorder)
african sickness sleeping
african sleeping sickness
african sleeping sicknesses
african trypanosoma nos
african trypanosomiases
african trypanosomiasis (disorder)
african trypanosomiasis nos
african trypanosomiasis nos (disorder)
african trypanosomiasis, unspecified
maladie du sommeil
schlafkrankheit
sickness sleeping
sickness, african sleeping
sicknesses, african sleeping
sleeping sickness
sleeping sickness nos
sleeping sickness, african
sleeping sickness, nos
sleeping sicknesses, african
trypanosomiases, african
trypanosomiasis, african
trypanosomiasis, african [disease/finding]
Orphanet
DOID
ICD10
UMLS
C0041228
MeSH
SNOMED-CT
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:9)
Curated Gene(Waiting for update.)
Inferring Gene
Entrez_id | Symbol | Resource(Total Genes:2)
3586  |  IL10  |  CIPHER
7124  |  TNF  |  CIPHER
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:122)
50808  |  AK3  |  2.358  |  DISEASES
205  |  AK4  |  1.954  |  DISEASES
501  |  ALDH7A1  |  1.731  |  DISEASES
262  |  AMD1  |  3.991  |  DISEASES
60489  |  APOBEC3G  |  1.198  |  DISEASES
522  |  ATP5J  |  1.358  |  DISEASES
7917  |  BAG6  |  2.044  |  DISEASES
57545  |  CC2D2A  |  1.969  |  DISEASES
911  |  CD1C  |  1.315  |  DISEASES
912  |  CD1D  |  1.418  |  DISEASES
344807  |  CD200R1L  |  3.608  |  DISEASES
51744  |  CD244  |  1.461  |  DISEASES
959  |  CD40LG  |  3.718  |  DISEASES
8760  |  CDS2  |  2.967  |  DISEASES
85301  |  COL27A1  |  3.669  |  DISEASES
8532  |  CPZ  |  4.014  |  DISEASES
1503  |  CTPS1  |  2.182  |  DISEASES
1506  |  CTRL  |  1.417  |  DISEASES
1508  |  CTSB  |  3.109  |  DISEASES
8454  |  CUL1  |  1.018  |  DISEASES
9937  |  DCLRE1A  |  1.932  |  DISEASES
23564  |  DDAH2  |  1.279  |  DISEASES
196385  |  DNAH10  |  3.434  |  DISEASES
1759  |  DNM1  |  1.102  |  DISEASES
1785  |  DNM2  |  1.097  |  DISEASES
9732  |  DOCK4  |  2.053  |  DISEASES
124454  |  EARS2  |  1.463  |  DISEASES
1984  |  EIF5A  |  1.686  |  DISEASES
2013  |  EMP2  |  1.621  |  DISEASES
377841  |  ENTPD8  |  2.193  |  DISEASES
132884  |  EVC2  |  1.213  |  DISEASES
2170  |  FABP3  |  1.322  |  DISEASES
2224  |  FDPS  |  2.688  |  DISEASES
342184  |  FMN1  |  1.144  |  DISEASES
2582  |  GALE  |  2.951  |  DISEASES
26301  |  GBGT1  |  1.773  |  DISEASES
2710  |  GK  |  1.54  |  DISEASES
51022  |  GLRX2  |  3.001  |  DISEASES
8833  |  GMPS  |  1.51  |  DISEASES
2804  |  GOLGB1  |  1.062  |  DISEASES
2821  |  GPI  |  1.012  |  DISEASES
2959  |  GTF2B  |  1.536  |  DISEASES
3005  |  H1F0  |  2.063  |  DISEASES
3098  |  HK1  |  2.604  |  DISEASES
3135  |  HLA-G  |  1.392  |  DISEASES
3240  |  HP  |  3.343  |  DISEASES
3250  |  HPR  |  5.406  |  DISEASES
3320  |  HSP90AA1  |  1.957  |  DISEASES
3586  |  IL10  |  2.839  |  DISEASES
253430  |  IPMK  |  2.156  |  DISEASES
3652  |  IPP  |  1.087  |  DISEASES
51477  |  ISYNA1  |  3.368  |  DISEASES
8564  |  KMO  |  1.489  |  DISEASES
51520  |  LARS  |  1.87  |  DISEASES
3963  |  LGALS7  |  1.644  |  DISEASES
225689  |  MAPK15  |  4.138  |  DISEASES
4190  |  MDH1  |  1.781  |  DISEASES
4199  |  ME1  |  2.026  |  DISEASES
57496  |  MKL2  |  2.097  |  DISEASES
54903  |  MKS1  |  1.979  |  DISEASES
4512  |  MT-CO1  |  2.053  |  DISEASES
4519  |  MT-CYB  |  1.406  |  DISEASES
4536  |  MT-ND2  |  1.99  |  DISEASES
26151  |  NAT9  |  1.735  |  DISEASES
58484  |  NLRC4  |  2.31  |  DISEASES
4843  |  NOS2  |  1.758  |  DISEASES
594857  |  NPS  |  1.334  |  DISEASES
4905  |  NSF  |  1.002  |  DISEASES
4923  |  NTSR1  |  2.632  |  DISEASES
8481  |  OFD1  |  1.516  |  DISEASES
164091  |  PAQR7  |  3.136  |  DISEASES
5144  |  PDE4D  |  2.034  |  DISEASES
10026  |  PIGK  |  3.035  |  DISEASES
9033  |  PKD2L1  |  1.768  |  DISEASES
11201  |  POLI  |  3.429  |  DISEASES
5464  |  PPA1  |  2.669  |  DISEASES
5550  |  PREP  |  1.325  |  DISEASES
58155  |  PTBP2  |  1.598  |  DISEASES
5770  |  PTPN1  |  1.059  |  DISEASES
8480  |  RAE1  |  2.691  |  DISEASES
57038  |  RARS2  |  1.958  |  DISEASES
1104  |  RCC1  |  1.433  |  DISEASES
7955  |  RNF217-AS1  |  2.328  |  DISEASES
6135  |  RPL11  |  1.541  |  DISEASES
6207  |  RPS13  |  1.133  |  DISEASES
6319  |  SCD  |  1.294  |  DISEASES
11231  |  SEC63  |  2.081  |  DISEASES
6906  |  SERPINA7  |  2.471  |  DISEASES
6418  |  SET  |  1.472  |  DISEASES
6580  |  SLC22A1  |  1.194  |  DISEASES
10478  |  SLC25A17  |  1.323  |  DISEASES
91137  |  SLC25A46  |  1.52  |  DISEASES
113235  |  SLC46A1  |  1.519  |  DISEASES
6594  |  SMARCA1  |  2.675  |  DISEASES
26806  |  SNORD44  |  2.126  |  DISEASES
200162  |  SPAG17  |  1.513  |  DISEASES
9576  |  SPAG6  |  2.173  |  DISEASES
6723  |  SRM  |  4.001  |  DISEASES
10250  |  SRRM1  |  1.708  |  DISEASES
8428  |  STK24  |  1.111  |  DISEASES
6863  |  TAC1  |  1.22  |  DISEASES
80222  |  TARS2  |  2.03  |  DISEASES
123283  |  TARSL2  |  2.067  |  DISEASES
55171  |  TBCCD1  |  3.764  |  DISEASES
10716  |  TBR1  |  3.294  |  DISEASES
84066  |  TEX35  |  3.444  |  DISEASES
7018  |  TF  |  2.793  |  DISEASES
7037  |  TFRC  |  1.518  |  DISEASES
8914  |  TIMELESS  |  1.69  |  DISEASES
10440  |  TIMM17A  |  3.718  |  DISEASES
7124  |  TNF  |  2.853  |  DISEASES
51592  |  TRIM33  |  2.022  |  DISEASES
5756  |  TWF1  |  3.621  |  DISEASES
7295  |  TXN  |  1.008  |  DISEASES
7306  |  TYRP1  |  1.486  |  DISEASES
51271  |  UBAP1  |  1.295  |  DISEASES
2837  |  UTS2R  |  1.644  |  DISEASES
57176  |  VARS2  |  2.273  |  DISEASES
6944  |  VPS72  |  2.223  |  DISEASES
23038  |  WDTC1  |  2.725  |  DISEASES
79971  |  WLS  |  1.41  |  DISEASES
9278  |  ZBTB22  |  1.036  |  DISEASES
Locus(Waiting for update.)
Disease ID 784
Disease african trypanosomiasis
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:3)
Disease ID 784
Disease african trypanosomiasis
Manually Symptom
UMLS  | Name(Total Manually Symptoms:13)
C2364072  |  depression
C1963101  |  encephalopathy
C1373218  |  immunosuppression
C1000483  |  anemia
C0752303  |  urological manifestations
C0476270  |  cardiovascular symptoms
C0348024  |  thyroid dysfunction
C0085584  |  encephalopathies
C0038454  |  stroke
C0026976  |  transverse myelitis
C0021053  |  immune dysfunction
C0014038  |  encephalitis
C0002871  |  anaemia
Text Mined Symptom
UMLS | Name | Sentences' Count(Total Symptoms:3)
C0752303  |  urological manifestations  |  1
C0085584  |  encephalopathy  |  1
C0038454  |  stroke  |  1
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
Text Mining Genotype(Total Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:0)
(Waiting for update.)
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Disease ID 784
Disease african trypanosomiasis
Case(Waiting for update.)